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The specificity of BTMs for bone cell activities has markedly increased over recent times. Their role for providing prognostic information on risk of fracture is uncertain however.

Recent evidence confirms their usefulness for monitoring response to antiresorptive therapies for osteoporosis. Robust assays for many markers have been adapted to automated biochemical platforms making them rapidly and cost-effectively available in clinical laboratories. They divide into two main categories, markers of bone cells and type I collagen formation or breakdown products. University of South Australia and SA Pathology, Adelaide, South Australia, AustraliaĬhair, IFCC-IOF WG for Standardisation of Bone Marker AssaysĪ wide range of biochemical markers provide information on the activities of bone cells, largely osteoclasts and osteoblasts, commonly termed bone turnover markers (BTM).

Wednesday, September 21 st, 2016 Pre-congress symposium Clinical utility of bone markers measurement in metabolic diseases Invited Speakers Clinical usefulness of bone turnover marker levels in osteoporosis: 2016 update

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